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The oxycodone in oxycodone HCl may possibly boost the frequency of seizures in individuals with seizure Issues, and could boost the chance of seizures happening in other medical configurations affiliated with seizures.In all patients for whom dosing facts was obtainable (n=191) with the open up-label and double-blind reports involving oxycodone HCl

The concomitant utilization of oxycodone HCl with all cytochrome P450 3A4 inhibitors may perhaps bring about an increase in oxycodone plasma concentrations, which could maximize or prolong adverse reactions and may trigger probably deadly respiratory melancholy. Moreover, discontinuation of a concomitantly utilised cytochrome P450 3A4 inducer could